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Analysis of Response Profiles of Adjusted Changes from Baseline |
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Treatment of Lead Exposed Children (TLC) Trial |
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The Mixed Procedure |
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Model Information |
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|
Data Set |
WORK.TLC |
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Dependent Variable |
change |
|
Covariance Structure |
Unstructured |
|
Subject Effect |
id |
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Estimation Method |
REML |
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Residual Variance Method |
None |
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Fixed Effects SE Method |
Model-Based |
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Degrees of Freedom Method |
Between-Within |
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Class Level Information |
||
|
Class |
Levels |
Values |
|
id |
100 |
not printed |
|
time |
3 |
1 4 6 |
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Dimensions |
|
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Covariance Parameters |
6 |
|
Columns in X |
7 |
|
Columns in Z |
0 |
|
Subjects |
100 |
|
Max Obs Per Subject |
3 |
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Observations Used |
300 |
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Observations Not Used |
0 |
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Total Observations |
300 |
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Iteration History |
|||
|
Iteration |
Evaluations |
-2 Res Log Like |
Criterion |
|
0 |
1 |
1895.77152040 |
|
|
1 |
2 |
1817.56562756 |
0.00000000 |
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Convergence criteria met. |
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Estimated R Matrix for id 1 |
|||
|
Row |
Col1 |
Col2 |
Col3 |
|
1 |
30.1509 |
20.8640 |
12.9909 |
|
2 |
20.8640 |
32.2303 |
13.4600 |
|
3 |
12.9909 |
13.4600 |
39.4775 |
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Fit Statistics |
|
|
-2 Res Log Likelihood |
1817.6 |
|
AIC (smaller is better) |
1829.6 |
|
AICC (smaller is better) |
1829.9 |
|
BIC (smaller is better) |
1845.2 |
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Solution for Fixed Effects |
|||||
|
Effect |
Estimate |
Standard Error |
DF |
t Value |
Pr > |t| |
|
Intercept |
-1.6382 |
0.7766 |
97 |
-2.11 |
0.0375 |
|
cbaseline |
-0.1955 |
0.09390 |
97 |
-2.08 |
0.0400 |
|
succimer |
-11.3536 |
1.0985 |
97 |
-10.34 |
<.0001 |
|
t4 |
-0.5900 |
0.6427 |
97 |
-0.92 |
0.3609 |
|
t6 |
-1.0140 |
0.9343 |
97 |
-1.09 |
0.2805 |
|
succimer*t4 |
2.5820 |
0.9089 |
97 |
2.84 |
0.0055 |
|
succimer*t6 |
8.2540 |
1.3213 |
97 |
6.25 |
<.0001 |
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Contrasts |
||||||
|
Label |
Num DF |
Den DF |
Chi-Square |
F Value |
Pr > ChiSq |
Pr > F |
|
3 DF Test of Main Effect and Interaction |
3 |
97 |
111.13 |
37.04 |
<.0001 |
<.0001 |