|
Analysis of Response Profiles of Changes from Baseline |
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Treatment of Lead Exposed Children (TLC) Trial |
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The Mixed Procedure |
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Model Information |
|
|
Data Set |
WORK.TLC |
|
Dependent Variable |
change |
|
Covariance Structure |
Unstructured |
|
Subject Effect |
id |
|
Estimation Method |
REML |
|
Residual Variance Method |
None |
|
Fixed Effects SE Method |
Model-Based |
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Degrees of Freedom Method |
Between-Within |
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Class Level Information |
||
|
Class |
Levels |
Values |
|
id |
100 |
not printed |
|
time |
3 |
1 4 6 |
|
Dimensions |
|
|
Covariance Parameters |
6 |
|
Columns in X |
6 |
|
Columns in Z |
0 |
|
Subjects |
100 |
|
Max Obs Per Subject |
3 |
|
Observations Used |
300 |
|
Observations Not Used |
0 |
|
Total Observations |
300 |
|
Iteration History |
|||
|
Iteration |
Evaluations |
-2 Res Log Like |
Criterion |
|
0 |
1 |
1900.36481189 |
|
|
1 |
1 |
1818.91458467 |
0.00000000 |
|
Convergence criteria met. |
|
Estimated R Matrix for id 1 |
|||
|
Row |
Col1 |
Col2 |
Col3 |
|
1 |
31.3566 |
21.9539 |
13.5917 |
|
2 |
21.9539 |
33.2046 |
13.9451 |
|
3 |
13.5917 |
13.9451 |
39.4735 |
|
Fit Statistics |
|
|
-2 Res Log Likelihood |
1818.9 |
|
AIC (smaller is better) |
1830.9 |
|
AICC (smaller is better) |
1831.2 |
|
BIC (smaller is better) |
1846.5 |
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Solution for Fixed Effects |
|||||
|
Effect |
Estimate |
Standard Error |
DF |
t Value |
Pr > |t| |
|
Intercept |
-1.6120 |
0.7919 |
98 |
-2.04 |
0.0445 |
|
succimer |
-11.4060 |
1.1199 |
98 |
-10.18 |
<.0001 |
|
t4 |
-0.5900 |
0.6427 |
98 |
-0.92 |
0.3609 |
|
t6 |
-1.0140 |
0.9343 |
98 |
-1.09 |
0.2805 |
|
succimer*t4 |
2.5820 |
0.9089 |
98 |
2.84 |
0.0055 |
|
succimer*t6 |
8.2540 |
1.3213 |
98 |
6.25 |
<.0001 |
|
Contrasts |
||||||
|
Label |
Num DF |
Den DF |
Chi-Square |
F Value |
Pr > ChiSq |
Pr > F |
|
3 DF Test of Main Effect and Interaction |
3 |
98 |
107.79 |
35.93 |
<.0001 |
<.0001 |