|
Analysis of Response Profiles assuming Equal Mean Blood Lead Levels at Baseline |
|
in the Succimer and Placebo Groups |
|
Treatment of Lead Exposed Children (TLC) Trial |
|
The Mixed Procedure |
|
Model Information |
|
|
Data Set |
WORK.TLC |
|
Dependent Variable |
y |
|
Covariance Structure |
Unstructured |
|
Subject Effect |
id |
|
Estimation Method |
REML |
|
Residual Variance Method |
None |
|
Fixed Effects SE Method |
Model-Based |
|
Degrees of Freedom Method |
Between-Within |
|
Class Level Information |
||
|
Class |
Levels |
Values |
|
id |
100 |
not printed |
|
time |
4 |
0 1 4 6 |
|
Dimensions |
|
|
Covariance Parameters |
10 |
|
Columns in X |
7 |
|
Columns in Z |
0 |
|
Subjects |
100 |
|
Max Obs Per Subject |
4 |
|
Observations Used |
400 |
|
Observations Not Used |
0 |
|
Total Observations |
400 |
|
Iteration History |
|||
|
Iteration |
Evaluations |
-2 Res Log Like |
Criterion |
|
0 |
1 |
2628.69582475 |
|
|
1 |
2 |
2417.98960808 |
0.00000001 |
|
Convergence criteria met. |
|
Estimated R Matrix for id 1 |
||||
|
Row |
Col1 |
Col2 |
Col3 |
Col4 |
|
1 |
24.9857 |
18.9281 |
19.5146 |
21.9933 |
|
2 |
18.9281 |
44.2074 |
35.3925 |
29.5142 |
|
3 |
19.5146 |
35.3925 |
47.2307 |
30.4547 |
|
4 |
21.9933 |
29.5142 |
30.4547 |
58.4642 |
|
Fit Statistics |
|
|
-2 Res Log Likelihood |
2418.0 |
|
AIC (smaller is better) |
2438.0 |
|
AICC (smaller is better) |
2438.6 |
|
BIC (smaller is better) |
2464.0 |
|
Solution for Fixed Effects |
|||||
|
Effect |
Estimate |
Standard Error |
DF |
t Value |
Pr > |t| |
|
Intercept |
26.4060 |
0.4999 |
99 |
52.83 |
<.0001 |
|
t1 |
-1.6445 |
0.7823 |
99 |
-2.10 |
0.0381 |
|
t4 |
-2.2313 |
0.8073 |
99 |
-2.76 |
0.0068 |
|
t6 |
-2.6420 |
0.8864 |
99 |
-2.98 |
0.0036 |
|
t1*succimer |
-11.3410 |
1.0930 |
99 |
-10.38 |
<.0001 |
|
t4*succimer |
-8.7653 |
1.1312 |
99 |
-7.75 |
<.0001 |
|
t6*succimer |
-3.1199 |
1.2507 |
99 |
-2.49 |
0.0143 |
|
Contrasts |
||||||
|
Label |
Num DF |
Den DF |
Chi-Square |
F Value |
Pr > ChiSq |
Pr > F |
|
3 DF Test of Interaction |
3 |
99 |
111.96 |
37.32 |
<.0001 |
<.0001 |