GEE Estimation of Marginal Log-linear Regression Model (Random Intercept and Slope)
Analysis Excluding Patient 49 (Potential Outlier)
Clinical Trial of Epileptic Patients

The GENMOD Procedure

Model Information
Data Set WORK.SEIZURE
Distribution Poisson
Link Function Log
Dependent Variable y
Offset Variable ltime

Number of Observations Read 290
Number of Observations Used 290

Class Level Information
Class Levels Values
id 58 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 50 51 52 53 54 55 56 57 58 59
visit 5 0 1 2 3 4

Parameter Information
Parameter Effect
Prm1 Intercept
Prm2 time
Prm3 trt
Prm4 time*trt

Algorithm converged.

GEE Model Information
Correlation Structure Unstructured
Within-Subject Effect visit (5 levels)
Subject Effect id (58 levels)
Number of Clusters 58
Correlation Matrix Dimension 5
Maximum Cluster Size 5
Minimum Cluster Size 5

Algorithm converged.

GEE Fit Criteria
QIC -1039.4724
QICu -1044.9820

Analysis Of GEE Parameter Estimates
Empirical Standard Error Estimates
Parameter Estimate Standard Error 95% Confidence Limits Z Pr > |Z|
Intercept 1.3312 0.1611 1.0154 1.6470 8.26 <.0001
time 0.1141 0.0926 -0.0675 0.2956 1.23 0.2181
trt -0.1021 0.1959 -0.4860 0.2819 -0.52 0.6023
time*trt -0.3167 0.1494 -0.6096 -0.0239 -2.12 0.0340