Data on serum cholesterol from the National Cooperative Gallstone Study (NCGS). Source: Table 2 (page 657) of Wei and Lachin (1984). Reproduced with permission of the American Statistical Association. Reference: Wei, L.J. and Lachin, J.M. (1984). Two-Sample Asymptotically Distribution-Free Tests for Incomplete Multivariate Observations. Journal of the American Statistical Association, 79, 653-661. Description: The data are from the National Cooperative Gallstone Study (NCGS), where one of the major interests was to study the safety of the drug chenodiol for the treatment of cholesterol gallstones In this study, patients were randomly assigned to high-dose (750 mg per day), low-dose (375 mg per day), or placebo. This dataset consists of a subset of data on patients who had floating gallstones and who were assigned to the high-dose and placebo groups. In the NCGS it was suggested that chenodiol would dissolve gallstones but in doing so might increase levels of serum cholesterol. As a result, serum cholesterol (mg/dL) was measured at baseline and at 6, 12, 20, and 24 months of follow-up. Many cholesterol measurements are missing because of missed visits, laboratory specimens were lost or inadequate, or patient follow-up was terminated. Variable List: Treatment Group (1=High dose chenodiol, 2-Placebo), Subject ID, Response at Baseline, Response at Month 6, Response at Month 12, Response at Month 20, Response at Month 24. Note: Response = Serum cholesterol (. denotes missing value). 1 1 178 246 295 228 274 1 2 254 260 278 245 340 1 3 185 232 215 220 292 1 4 219 268 241 260 320 1 5 205 232 265 242 230 1 6 182 213 173 200 193 1 7 310 334 290 286 248 1 8 191 204 227 228 196 1 9 245 270 209 255 213 1 10 229 200 238 259 221 1 11 245 293 261 297 231 1 12 240 313 251 307 291 1 13 234 281 277 235 210 1 14 210 252 275 235 237 1 15 275 231 285 238 251 1 16 269 332 300 320 335 1 17 148 180 184 231 184 1 18 181 194 212 217 205 1 19 165 242 250 249 312 1 20 293 276 276 278 306 1 21 195 190 205 217 238 1 22 210 230 249 240 194 1 23 212 224 246 271 256 1 24 243 271 304 273 318 1 25 259 279 296 262 283 1 26 202 214 192 239 172 1 27 184 192 205 253 217 1 28 238 272 297 282 251 1 29 263 283 248 334 271 1 30 144 226 261 227 283 1 31 220 272 222 246 253 1 32 225 260 253 202 265 1 33 224 273 242 274 . 1 34 307 252 316 258 283 1 35 313 300 313 317 397 1 36 231 252 267 299 . 1 37 206 177 194 194 212 1 38 285 291 291 268 260 1 39 250 269 . . . 1 40 175 214 . . . 1 41 201 219 220 . . 1 42 268 296 314 330 . 1 43 202 186 253 . . 1 44 260 268 . . . 1 45 209 207 167 . . 1 46 197 218 . . . 1 47 248 262 . . . 1 48 212 253 225 . . 1 49 276 326 304 . . 1 50 163 179 199 . . 1 51 239 243 265 . . 1 52 204 203 198 . . 1 53 247 211 225 . . 1 54 195 250 272 . . 1 55 228 228 279 . . 1 56 290 264 260 . . 1 57 284 288 268 261 . 1 58 217 231 276 257 . 1 59 209 200 269 233 . 1 60 200 261 264 300 . 1 61 227 247 . . 220 1 62 193 189 . 232 211 2 63 251 262 239 234 248 2 64 233 218 230 251 273 2 65 250 258 258 286 240 2 66 141 143 157 162 169 2 67 418 371 363 384 387 2 68 229 218 228 244 179 2 69 271 289 270 296 346 2 70 312 323 318 383 310 2 71 194 220 214 256 204 2 72 211 232 189 230 231 2 73 205 299 278 259 266 2 74 191 248 283 268 233 2 75 249 217 236 266 235 2 76 301 270 282 287 268 2 77 201 214 247 274 224 2 78 251 257 237 266 . 2 79 277 242 249 293 306 2 80 294 313 295 295 271 2 81 212 236 235 272 287 2 82 230 315 300 305 341 2 83 206 242 236 239 . 2 84 246 205 249 225 236 2 85 245 192 215 214 242 2 86 179 202 194 239 234 2 87 165 142 188 192 200 2 88 262 274 245 275 278 2 89 212 216 228 221 223 2 90 285 292 300 319 277 2 91 166 171 166 186 220 2 92 179 206 214 189 250 2 93 298 280 280 328 318 2 94 238 267 269 268 280 2 95 172 180 216 183 . 2 96 191 208 162 218 206 2 97 282 282 . . . 2 98 213 249 219 209 . 2 99 171 188 . . . 2 100 242 268 . . . 2 101 197 224 214 . . 2 102 230 228 266 . . 2 103 373 309 332 . .